SCHEMBL29059754

SCHEMBL29059754

CC1(Cc2ccccc2)OO1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
ELANE P08246 4/20 0.42
TP53 P04637 1/20 0.42
CALM1 P0DP23 1/20 0.39
ANPEP P15144 1/20 0.37
LAP3 P28838 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
AKR1B1 P15121 1/20 0.37
MMP2 P08253 2/20 0.37
MMP9 P14780 2/20 0.37
MMP8 P22894 2/20 0.37
MMP13 P45452 2/20 0.37
OPRM1 P35372 1/20 0.36
OPRK1 P41145 1/20 0.36
OPRL1 P41146 1/20 0.36
CTSG P08311 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1680374 0.81 ELANE (0.40) MAOAMAOBELANETP53CALM1
SCHEMBL8704294 0.79 MAOA (0.43) MAOAMAOBELANETP53TSHR
SCHEMBL14779392 0.76 MAPK1 (0.43) MAOAMAOBELANETP53ALDH1A1
SCHEMBL14778149 0.76 MAOA (0.41) MAOAMAOBELANETP53TSHR
SCHEMBL18805033 0.73 ELANE (0.42) MAOAMAOBELANEALDH1A1TSHR
SCHEMBL1587776 0.73 ELANE (0.42) MAOAMAOBELANEALDH1A1CTSG
SCHEMBL2525239 0.71 MAOA (0.45) MAOAMAOBELANETP53OPRM1
SCHEMBL5062845 0.71 MAOA (0.45) MAOAMAOBELANETP53OPRM1
SCHEMBL5065445 0.71 MAOA (0.45) MAOAMAOBELANETP53OPRM1
SCHEMBL2374703 0.70 MAOA (0.54) MAOAMAOBELANETP53CALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116637601-A Ion imprinting polymer material and application thereof 华北理工大学 2023-08-25 CN disclosed