Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.45 |
| ▸ | MAOB | P27338 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5062845 | 1.00 | MAOA (0.45) | MAOAMAOBGAAELANETP53 | |
| SCHEMBL2525239 | 1.00 | MAOA (0.45) | MAOAMAOBGAAELANETP53 | |
| Hydrochloric Acid SCHEMBL29078687 | 0.96 | MAOA (0.42) | MAOAMAOBGAAELANETP53 | |
| SCHEMBL14583504 | 0.86 | MAOA (0.38) | MAOAMAOBGAAELANETP53 | |
| SCHEMBL11058571 | 0.85 | MAOA (0.37) | MAOAMAOBGAAELANEOPRM1 | |
| SCHEMBL8615501 | 0.80 | HTR6 (0.47) | MAOA | |
| SCHEMBL7997821 | 0.78 | GAA (0.41) | MAOAMAOBGAAOPRM1OPRL1 | |
| SCHEMBL22013858 | 0.78 | GAA (0.41) | MAOAMAOBGAAOPRM1OPRL1 | |
| SCHEMBL23611125 | 0.76 | MAOA (0.48) | MAOAMAOBTP53OPRM1OPRK1 | |
| SCHEMBL28162658 | 0.76 | MAOA (0.48) | MAOAMAOBTP53OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756271-B1 | METHODS FOR OBTAINING OPTICALLY ACTIVE EPOXIDES AND VICINAL DIOLS FROM 2,2-DISUBSTITUTED EPOXIDES | CSIR (ZA) | 2015-12-09 | — | — | EP | disclosed |
| US-20080286832-A1 | Methods for Obtaining Optically Active Epoxides and Vicinal Diols From 2,2-Disubstituted Epoxides | COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH (ZA) | 2008-11-20 | — | — | US | disclosed |
| EP-1756271-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE EPOXIDES AND VICINAL DIOLS FROM 2,2-DISUBSTITUTED EPOXIDES | CSIR (ZA) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005100587-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE EPOXIDES AND VICINAL DIOLS FROM 2,2-DISUBSTITUTED EPOXIDES | CSIR (ZA) | 2005-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080286832-A1 | Methods for Obtaining Optically Active Epoxides and Vicinal Diols From 2,2-Disubstituted Epoxides | EPHX2, ERG28, DERA | MAOA 1212/4885MAOB 1403/4885GAA 352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.