Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24365642 | 0.85 | NR1H2 (0.39) | NR1H2CHRM2CHRM1CHRM3MAPT | |
| SCHEMBL24365332 | 0.81 | NR1H2 (0.37) | NR1H2CHRM2CHRM1CHRM3MAPT | |
| SCHEMBL25092184 | 0.80 | FAAH (0.36) | NR1H2CHRM2CHRM1CHRM3MAPT | |
| SCHEMBL24364142 | 0.80 | CHRM2 (0.41) | NR1H2CHRM2CHRM1CHRM3MAPT | |
| SCHEMBL15570996 | 0.80 | CHRM2 (0.41) | NR1H2CHRM2CHRM1CHRM3MAPT | |
| SCHEMBL25092185 | 0.79 | NR1H2 (0.35) | NR1H2CHRM2CHRM1CHRM3MAPT | |
| SCHEMBL29060382 | 0.79 | CHRM2 (0.39) | NR1H2CHRM2CHRM1CHRM3MAPT | |
| SCHEMBL25037249 | 0.79 | CHRM2 (0.41) | NR1H2CHRM2CHRM1CHRM3MAPT | |
| SCHEMBL29067864 | 0.78 | GLA (0.36) | NR1H2CHRM2CHRM1CHRM3MAPT | |
| SCHEMBL31126748 | 0.77 | ALDH1A1 (0.38) | NR1H2CHRM2CHRM1CHRM3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670143-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-08-29 | — | — | CN | disclosed |