SCHEMBL29060432

SCHEMBL29060432

N#Cc1ccc(Nc2cc3ccccc3s2)cc1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 14/20 0.49
ABCB1 P08183 10/20 0.49
ABCC1 P33527 4/20 0.44
EGFR P00533 1/20 0.43
KDR P35968 1/20 0.43
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
POLB P06746 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17194793 0.81 MAPT (0.46) MEN1NPC1RAB9AKMT2AALDH1A1
SCHEMBL28092300 0.79 APP (0.53) MEN1NPC1RAB9AKMT2AKDM4E
SCHEMBL6481877 0.77 CYP2A6 (0.47)
SCHEMBL1098482 0.76 KDM4E (0.52) KDM4E
SCHEMBL8049382 0.76 ADRA2A (0.42) KDRMEN1NPC1RAB9AKMT2A
SCHEMBL29060481 0.75 CSNK1D (0.41) ABCG2MEN1NPC1RAB9AKMT2A
SCHEMBL28829819 0.72 APP (0.62) ABCG2ABCB1
SCHEMBL21905659 0.72 MAPT (0.45) RAB9AALDH1A1
SCHEMBL14926283 0.71 ALDH1A1 (0.66) ABCG2ABCB1ABCC1EGFRKDR
SCHEMBL1821911 0.71 NPC1 (0.69) ABCG2ABCB1MEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116253749-A Compound and application thereof, and organic electroluminescent device comprising compound 北京鼎材科技有限公司 2023-06-13 CN disclosed