SCHEMBL29060751

SCHEMBL29060751

CC(=O)Nc1ccc(/C=C/C(=O)c2ccccn2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.68
NPC1 O15118 5/20 0.68
RAB9A P51151 5/20 0.68
MEN1 O00255 5/20 0.68
KMT2A Q03164 5/20 0.68
MAPK1 P28482 2/20 0.68
LMNA P02545 6/20 0.67
KDM4E B2RXH2 3/20 0.67
PKM P14618 3/20 0.67
ALDH1A1 P00352 3/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
TUBB4A P04350 1/20 0.62
TUBB P07437 1/20 0.62
TUBA3C P0DPH7 1/20 0.62
TUBA1B P68363 1/20 0.62
TUBA4A P68366 1/20 0.62
TUBB4B P68371 1/20 0.62
TUBB3 Q13509 1/20 0.62
TUBB2A Q13885 1/20 0.62
TUBB8 Q3ZCM7 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12257967 0.85 MAPT (0.90) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL29060752 0.85 NPC1 (0.52) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL8485080 0.81 MAPT (1.00) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL8485074 0.81 MAPT (1.00) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL9231011 0.81 MAPT (0.77) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL9231010 0.81 MAPT (0.77) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL4400320 0.81 MAPT (1.00) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL977480 0.81 MAPT (1.00) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL1320225 0.80 KDM4E (0.74) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL22009097 0.80 TUBB4A (0.68) MAPTNPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116408203-A Method for separating feldspar from photovoltaic glass quartz sand by lepidolite tailings 合肥万泉非金属矿科技有限公司 2023-07-11 CN claimed
CN-116408203-A Method for separating feldspar from photovoltaic glass quartz sand by lepidolite tailings 合肥万泉非金属矿科技有限公司 2023-07-11 CN disclosed