Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 6/20 | 0.50 |
| ▸ | NT5E | P21589 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 4/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7624342 | 0.90 | AHCY (0.50) | AHCYNT5ELMNAHIF1ACA5A | |
| SCHEMBL3328524 | 0.81 | AHCY (0.47) | AHCYNT5ELMNAHIF1ACA5A | |
| SCHEMBL16750272 | 0.76 | AHCY (0.38) | AHCYNT5ELMNAHIF1A | |
| SCHEMBL17040219 | 0.74 | AHCY (0.49) | AHCYNT5ELMNAHIF1ACA5A | |
| SCHEMBL23027205 | 0.73 | CDK1 (0.42) | AHCYADORA2AADORA1CDK1CCNB1 | |
| SCHEMBL130527 | 0.73 | CDK1 (0.64) | AHCYNT5ELMNAHIF1AADORA3 | |
| SCHEMBL10460432 | 0.72 | ADORA2A (0.46) | AHCYADORA2AADORA2BADORA1 | |
| SCHEMBL24434420 | 0.71 | AHCY (0.47) | AHCYNT5ELMNAHIF1ACA5A | |
| SCHEMBL27983442 | 0.71 | CDK1 (0.59) | AHCYADORA2AADORA2BADORA1CDK1 | |
| SCHEMBL24222088 | 0.70 | CDK1 (0.50) | AHCYNT5ELMNAHIF1ACA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116492347-A | Compound for activating AMPK and application thereof | 华安医学股份有限公司 | 2023-07-28 | — | — | CN | disclosed |