Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.46 |
| ▸ | PI4KA | P42356 | 5/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 5/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 5/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | AHCY | P23526 | 6/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580610 | 0.82 | ADORA2A (0.64) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL28413958 | 0.80 | ADORA2A (0.62) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL3506547 | 0.79 | ADORA2A (0.46) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL28410735 | 0.78 | ADORA2A (0.60) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL27983442 | 0.76 | CDK1 (0.59) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL7987866 | 0.74 | ADORA2A (0.35) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL556881 | 0.72 | XDH (0.50) | — | |
| SCHEMBL120720 | 0.72 | ADORA2A (0.49) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL29060920 | 0.72 | AHCY (0.50) | ADORA2AADORA1ADORA2BAHCY | |
| SCHEMBL27531530 | 0.72 | CDK2 (0.39) | ADORA2AAHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2235883-A | — | — | None | — | — | JP | disclosed |
| JP-H02235883-A | ISOMERIC DIDEOXYNUCLEOSIDE | F HOFFMANN LA ROCHE AG | 1990-09-18 | — | — | JP | disclosed |