Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29061005 | 0.85 | HPGD (0.54) | HPGDSMN1; SMN2POLBMAPTHTT | |
| SCHEMBL23412473 | 0.83 | HPGD (0.47) | HPGDSMN1; SMN2POLBMAPTHTT | |
| SCHEMBL30639190 | 0.74 | HPGD (0.69) | HPGDSMN1; SMN2POLBMAPTHTT | |
| SCHEMBL2422719 | 0.73 | TDP1 (0.73) | HPGDSMN1; SMN2POLBMAPTTP53 | |
| SCHEMBL19420131 | 0.71 | HPGD (0.71) | HPGDSMN1; SMN2POLBMAPTHTT | |
| SCHEMBL23440341 | 0.71 | SMN1; SMN2 (0.61) | HPGDSMN1; SMN2POLBMAPTHTT | |
| SCHEMBL12172824 | 0.70 | NPSR1 (0.72) | HPGDSMN1; SMN2POLBMAPTHTT | |
| SCHEMBL23413024 | 0.70 | ALDH1A1 (0.69) | HPGDSMN1; SMN2POLBMAPTHTT | |
| SCHEMBL30092886 | 0.70 | ALDH1A1 (0.69) | HPGDSMN1; SMN2POLBMAPTHTT | |
| SCHEMBL6358692 | 0.70 | HPGD (0.66) | HPGDSMN1; SMN2POLBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397806-A | Aryl and heteroaryl compounds and their therapeutic use in conditions associated with altered activity of galactocerebrosidase | 增益治疗股份有限公司 | 2022-11-25 | — | — | CN | disclosed |