Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 11/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29061003 | 0.85 | HPGD (0.52) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL23412473 | 0.85 | HPGD (0.47) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL23440346 | 0.72 | HPGD (0.56) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL30093081 | 0.71 | ALDH1A1 (0.71) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL23412458 | 0.71 | ALDH1A1 (0.71) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL12172824 | 0.69 | NPSR1 (0.72) | HPGDALDH1A1MAPTHSD17B10POLB | |
| SCHEMBL23412461 | 0.69 | KDM4E (0.72) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL30092907 | 0.69 | KDM4E (0.72) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL16676602 | 0.68 | HPGD (0.66) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL19747003 | 0.68 | HPGD (0.69) | HPGDALDH1A1MAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397806-A | Aryl and heteroaryl compounds and their therapeutic use in conditions associated with altered activity of galactocerebrosidase | 增益治疗股份有限公司 | 2022-11-25 | — | — | CN | disclosed |