Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 15/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29061635 | 0.94 | DGAT2 (0.56) | DGAT2KMT2AATMPIK3CAPRKDC | |
| SCHEMBL29061600 | 0.93 | DGAT2 (0.56) | DGAT2KMT2AATMPIK3CAPRKDC | |
| SCHEMBL25355871 | 0.89 | DGAT2 (0.72) | DGAT2KMT2AATM | |
| SCHEMBL25355875 | 0.89 | DGAT2 (0.63) | DGAT2KMT2AATMPIK3CAPRKDC | |
| SCHEMBL29061634 | 0.87 | DGAT2 (0.65) | DGAT2KMT2AATMNPC1RAB9A | |
| SCHEMBL29061632 | 0.86 | DGAT2 (0.67) | DGAT2KMT2AATMNPC1RAB9A | |
| SCHEMBL29061616 | 0.86 | DGAT2 (0.59) | DGAT2KMT2AATMNPC1RAB9A | |
| SCHEMBL25352294 | 0.84 | DGAT2 (0.65) | DGAT2KMT2A | |
| SCHEMBL25353133 | 0.84 | DGAT2 (0.65) | DGAT2KMT2A | |
| SCHEMBL25352299 | 0.84 | DGAT2 (0.59) | DGAT2KMT2AATMPIK3CAPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685577-A | Preparation of benzimidazolone derivatives as novel diacylglycerol O-acyltransferase 2 inhibitors | 默沙东有限责任公司 | 2023-09-01 | — | — | CN | claimed |
| CN-116685577-A | Preparation of benzimidazolone derivatives as novel diacylglycerol O-acyltransferase 2 inhibitors | 默沙东有限责任公司 | 2023-09-01 | — | — | CN | disclosed |