Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 14/20 | 0.42 |
| ▸ | PPARA | Q07869 | 13/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13210271 | 0.88 | PPARD (0.46) | PPARDPPARAFBP1PPARGL3MBTL1 | |
| SCHEMBL14534197 | 0.87 | PPARD (0.42) | PPARDPPARAFBP1PPARGL3MBTL1 | |
| SCHEMBL2907451 | 0.84 | RAB9A (0.39) | PPARDPPARAFBP1PPARGRAB9A | |
| SCHEMBL2900983 | 0.80 | PPARD (0.50) | PPARDPPARAPPARGRAB9ASMN1; SMN2 | |
| SCHEMBL3069062 | 0.77 | RAB9A (0.41) | PPARAFBP1PPARGRAB9AHPGD | |
| SCHEMBL4186855 | 0.77 | PPARD (0.55) | PPARDPPARAPPARGHPGDSMN1; SMN2 | |
| SCHEMBL28277544 | 0.77 | FBP1 (0.41) | PPARDPPARAFBP1PPARG | |
| SCHEMBL4399378 | 0.76 | RAB9A (0.50) | FBP1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL2904561 | 0.76 | RAB9A (0.43) | PPARAFBP1PPARGRAB9ASMN1; SMN2 | |
| SCHEMBL5186652 | 0.76 | FBP1 (0.54) | PPARDPPARAFBP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951692-B1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-08-18 | — | — | EP | disclosed |
| US-20100048453-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-02-25 | — | — | US | disclosed |
| US-20100048453-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-02-25 | — | — | US | disclosed |
| US-20100048453-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-02-25 | — | — | US | disclosed |
| US-20090192203-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2009-07-30 | — | — | US | disclosed |
| EP-1951692-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2008-08-06 | — | — | EP | disclosed |
| EP-1945620-A2 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007056366-A2 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056496-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048453-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | PPARD, PPARG, PPARA | PPARD 1/4885PPARA 3/4885FBP1 929/4885 |
| US-20090192203-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | PPARG, PPARA, PPARD | PPARD 3/4885PPARA 2/4885FBP1 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.