Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307869 | 0.84 | IDO1 (0.41) | TP53IDO1TDO2 | |
| SCHEMBL791595 | 0.80 | IDO1 (0.44) | HSD17B2TSHRCNR2IDO1TDO2 | |
| SCHEMBL9388011 | 0.80 | CNR2 (0.35) | CNR2 | |
| SCHEMBL10592795 | 0.79 | ADRA2A (0.41) | MAPTSCN1ASCN2ASCN3ATSHR | |
| SCHEMBL6970391 | 0.78 | HSD17B2 (0.45) | MAPTHSD17B2TSHR | |
| SCHEMBL461448 | 0.76 | IDO1 (0.47) | SCN1ASCN2ASCN3ATSHROPRM1 | |
| SCHEMBL10335667 | 0.75 | ALDH1A1 (0.42) | TSHR | |
| SCHEMBL23296602 | 0.74 | IDO1 (0.46) | SCN1ASCN2ASCN3ATSHROPRM1 | |
| SCHEMBL6563562 | 0.74 | HTT (0.43) | MAPTTP53TSHROPRM1OPRD1 | |
| SCHEMBL31065464 | 0.73 | MAPT (0.57) | MAPTTP53TSHROPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190187532-A1 | ELECTROCHROMIC DEVICES AND METHODS OF MAKING AND USE THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2019-06-20 | — | — | US | claimed |
| CN-107629033-A | A kind of synthetic method of [60] fullerene benzothiophene derivative that DDQ promotes | 河南师范大学 | 2018-01-26 | — | — | CN | claimed |
| EP-0032432-B1 | PROSTANOID COMPOUNDS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS | GLAXO GROUP LIMITED (GB) | 1985-07-24 | — | — | EP | claimed |
| US-4438111-A | PROSTAGLANDINS, ANTICOAGULANTS, ANTIASTHMA | GLAXO GROUP LIMITED (GB) | 1984-03-20 | — | — | US | claimed |
| EP-0032432-A1 | Prostanoid compounds and their preparation and pharmaceutical formulations | GLAXO GROUP LIMITED (GB) | 1981-07-22 | — | — | EP | claimed |
| US-20190187532-A1 | ELECTROCHROMIC DEVICES AND METHODS OF MAKING AND USE THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2019-06-20 | — | — | US | disclosed |
| WO-2013041482-A1 | SIDE CHAIN-FUNCTIONALIZED PEG | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (DE) | 2013-03-28 | — | — | WO | disclosed |
| EP-2220081-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG Life Sciences Ltd. (KR) | 2010-08-25 | — | — | EP | disclosed |
| EP-2155258-A1 | IMPROVED PROCESSES FOR MAKING HYDRAZIDES | Wyeth LLC (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2009082152-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG LIFE SCIENCES LTD. (KR) | 2009-07-02 | — | — | WO | disclosed |
| WO-2008147765-A1 | IMPROVED PROCESSES FOR MAKING HYDRAZIDES | WYETH (US) | 2008-12-04 | — | — | WO | disclosed |
| CN-1250528-C | Cyclic nitrones and pharmaceutical compositions containing them | AWENTIS PHARMACEUTICAL INC (US) | 2006-04-12 | — | — | CN | disclosed |
| CN-1500787-A | Cyclic nitrones and pharmaceutical compositions containing them | ���µ�˹ҩ�﹫˾ | 2004-06-02 | — | — | CN | disclosed |
| CN-1500779-A | Cyclic nitrones and pharmaceutical compositions containing them | ���µ�˹ҩ�﹫˾ | 2004-06-02 | — | — | CN | disclosed |
| CN-1308608-A | Substituted beta-amino acid inhibitors of methionine aminopeptidase-2 | ABBOTT LAB (US) | 2001-08-15 | — | — | CN | disclosed |
| CN-1196050-A | Cyclic nitrones and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (US) | 1998-10-14 | — | — | CN | disclosed |
| EP-0032432-B1 | PROSTANOID COMPOUNDS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS | GLAXO GROUP LIMITED (GB) | 1985-07-24 | — | — | EP | disclosed |
| US-4438111-A | PROSTAGLANDINS, ANTICOAGULANTS, ANTIASTHMA | GLAXO GROUP LIMITED (GB) | 1984-03-20 | — | — | US | disclosed |
| EP-0032432-A1 | Prostanoid compounds and their preparation and pharmaceutical formulations | GLAXO GROUP LIMITED (GB) | 1981-07-22 | — | — | EP | disclosed |