Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19330972 | 0.89 | ADORA2A (0.41) | KDM4ELMNAKMT2AJAK2TLR2 | |
| SCHEMBL19343377 | 0.89 | ADORA2A (0.41) | KDM4ELMNAKMT2AJAK2TLR2 | |
| SCHEMBL19331154 | 0.88 | POLB (0.34) | KDM4ELMNAPKMKMT2ANPC1 | |
| SCHEMBL19331152 | 0.88 | POLB (0.34) | KDM4ELMNAPKMKMT2ANPC1 | |
| SCHEMBL19330913 | 0.85 | POLB (0.34) | KDM4ELMNAPKMKMT2ANPC1 | |
| SCHEMBL23852915 | 0.84 | POLB (0.46) | LMNAKMT2ANPC1MAPTPOLB | |
| SCHEMBL19331175 | 0.84 | POLB (0.46) | LMNAKMT2ANPC1MAPTPOLB | |
| SCHEMBL19331172 | 0.84 | POLB (0.46) | LMNAKMT2ANPC1MAPTPOLB | |
| SCHEMBL19332733 | 0.83 | MEN1 (0.32) | KDM4ELMNAKMT2AHTTSMN1; SMN2 | |
| SCHEMBL19332730 | 0.83 | MEN1 (0.32) | KDM4ELMNAKMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685576-A | Cysteine protease inhibitors and methods of use thereof | 美商帕迪斯生物科学公司 | 2023-09-01 | — | — | CN | disclosed |