Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1359072 | 0.85 | ESR1 (0.51) | ESR1ESR2 | |
| SCHEMBL1359779 | 0.85 | ESR1 (0.51) | ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL2183048 | 0.84 | ESR1 (0.51) | ESR1ESR2 | |
| SCHEMBL5418196 | 0.78 | ESR1 (0.49) | ESR1ESR2 | |
| SCHEMBL5706948 | 0.77 | LTA4H (0.39) | — | |
| Hydrochloric Acid SCHEMBL3111360 | 0.76 | ESR1 (0.61) | ESR1ESR2 | |
| SCHEMBL1359755 | 0.75 | ESR1 (0.50) | ESR1ESR2 | |
| SCHEMBL2180952 | 0.74 | ESR1 (0.62) | ESR1ESR2 | |
| SCHEMBL3115415 | 0.73 | LTA4H (0.52) | ESR1ESR2 | |
| SCHEMBL9939378 | 0.71 | SLC2A1 (0.42) | SLC2A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709021-B1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS FOR THE TREATMENT OF VASOMOTOR SYMPTOMS | LILLY CO ELI (US) | 2010-08-04 | — | — | EP | disclosed |