Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 17/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1359779 | 0.93 | ESR1 (0.51) | ESR1ESR2 | |
| SCHEMBL1359072 | 0.93 | ESR1 (0.51) | ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL2183048 | 0.92 | ESR1 (0.51) | ESR1ESR2 | |
| SCHEMBL1359755 | 0.88 | ESR1 (0.50) | ESR1ESR2 | |
| SCHEMBL2180952 | 0.88 | ESR1 (0.62) | ESR1ESR2 | |
| SCHEMBL3115415 | 0.86 | LTA4H (0.52) | ESR1ESR2LTA4H | |
| SCHEMBL1358434 | 0.79 | ESR1 (0.51) | ESR1ESR2LTA4H | |
| SCHEMBL1358193 | 0.79 | ESR1 (0.54) | ESR1ESR2LTA4H | |
| SCHEMBL1358420 | 0.79 | ESR1 (0.54) | ESR1ESR2LTA4H | |
| SCHEMBL2906308 | 0.78 | ESR1 (0.35) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070111988-A1 | Selective estrogen receptor modulators | ELI LILLY AND COMPANY (US) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070111988-A1 | Selective estrogen receptor modulators | ESR2, GPER1, ESRRA | ESR1 5/4885ESR2 1/4885LTA4H 1532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.