Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29063142 | 0.84 | RAB9A (0.61) | KMT2APOLBRAB9ANPC1MEN1 | |
| SCHEMBL25768183 | 0.83 | POLB (0.54) | KMT2APOLBRAB9ANPC1MEN1 | |
| SCHEMBL23836100 | 0.82 | KMT2A (0.57) | KMT2APOLBRAB9ANPC1MEN1 | |
| SCHEMBL30310677 | 0.80 | SRD5A2 (0.67) | KMT2APOLBRAB9ANPC1MEN1 | |
| SCHEMBL24020490 | 0.80 | SRD5A2 (0.67) | KMT2APOLBRAB9ANPC1MEN1 | |
| SCHEMBL914072 | 0.80 | SMYD3 (0.47) | KMT2APOLBRAB9ANPC1MEN1 | |
| SCHEMBL29062822 | 0.79 | SRD5A2 (0.52) | KMT2APOLBRAB9ANPC1MEN1 | |
| Hydrochloric Acid SCHEMBL916268 | 0.79 | SMYD3 (0.46) | KMT2APOLBRAB9ANPC1MEN1 | |
| SCHEMBL914457 | 0.78 | SMYD3 (0.44) | KMT2APOLBRAB9ANPC1MEN1 | |
| SCHEMBL6962173 | 0.77 | HTR7 (0.47) | KMT2APOLBRAB9ANPC1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685576-A | Cysteine protease inhibitors and methods of use thereof | 美商帕迪斯生物科学公司 | 2023-09-01 | — | — | CN | disclosed |