Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24113423 | 1.00 | NR1H2 (0.40) | NR1H2CHRM2CHRM1CHRM3CYP1A2 | |
| SCHEMBL29063178 | 1.00 | NR1H2 (0.40) | NR1H2CHRM2CHRM1CHRM3CYP1A2 | |
| SCHEMBL31567936 | 0.90 | MMP2 (0.43) | NR1H2CHRM2CHRM1CHRM3CYP1A2 | |
| SCHEMBL2253790 | 0.90 | MMP2 (0.43) | NR1H2CHRM2CHRM1CHRM3CYP1A2 | |
| SCHEMBL6848252 | 0.90 | MMP2 (0.43) | NR1H2CHRM2CHRM1CHRM3CYP1A2 | |
| SCHEMBL23216338 | 0.90 | MMP2 (0.43) | NR1H2CHRM2CHRM1CHRM3CYP1A2 | |
| SCHEMBL6848250 | 0.90 | MMP2 (0.43) | NR1H2CHRM2CHRM1CHRM3CYP1A2 | |
| SCHEMBL2251657 | 0.90 | MMP2 (0.43) | NR1H2CHRM2CHRM1CHRM3CYP1A2 | |
| SCHEMBL7414498 | 0.87 | HSD17B10 (0.43) | NR1H2CHRM2CHRM1CHRM3CYP1A2 | |
| SCHEMBL30768193 | 0.87 | HSD17B10 (0.43) | NR1H2CHRM2CHRM1CHRM3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685576-A | Cysteine protease inhibitors and methods of use thereof | 美商帕迪斯生物科学公司 | 2023-09-01 | — | — | CN | disclosed |