Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414502 | 1.00 | HSD17B10 (0.43) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL30768193 | 1.00 | HSD17B10 (0.43) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL29063180 | 1.00 | HSD17B10 (0.43) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL24113423 | 0.87 | NR1H2 (0.40) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL29063175 | 0.87 | NR1H2 (0.40) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL29063178 | 0.87 | NR1H2 (0.40) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL25929622 | 0.84 | HSD17B10 (0.48) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL2273886 | 0.84 | HSD17B10 (0.48) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL2251657 | 0.84 | MMP2 (0.43) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL31567936 | 0.84 | MMP2 (0.43) | HSD17B10NR1H2CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4501901-A | Method for making substituted prolines | E. R. SQUIBB & SONS, INC. (US) | 1985-02-26 | — | — | US | disclosed |