Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.52 |
| ▸ | FCER2 | P06734 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | MMP8 | P22894 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906870 | 0.89 | TACR1 (0.53) | TACR1FCER2MMP9MMP8CTSL | |
| SCHEMBL2900007 | 0.89 | TACR1 (0.53) | TACR1FCER2MMP9MMP8CTSL | |
| SCHEMBL2900002 | 0.89 | TACR1 (0.53) | TACR1FCER2MMP9MMP8CTSL | |
| SCHEMBL1554667 | 0.82 | CTSL (0.60) | FCER2MMP9MMP8CTSLCTSS | |
| SCHEMBL2905617 | 0.82 | CTSL (0.60) | FCER2MMP9MMP8CTSLCTSS | |
| SCHEMBL1554664 | 0.82 | CTSL (0.60) | FCER2MMP9MMP8CTSLCTSS | |
| SCHEMBL2903014 | 0.77 | CTSL (0.54) | TACR1FCER2MMP9MMP8CTSL | |
| SCHEMBL2903010 | 0.77 | CTSL (0.54) | TACR1FCER2MMP9MMP8CTSL | |
| SCHEMBL2903642 | 0.77 | CTSL (0.54) | TACR1FCER2MMP9MMP8CTSL | |
| SCHEMBL29936235 | 0.76 | NLRP3 (0.68) | KMT2AMEN1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763507-B1 | ALPHA-AMINO ACID DERIVATES WITH ANTIINFLAMMATORY ACTIVITY | ITALFARMACO SPA (IT) | 2010-08-11 | — | — | EP | claimed |