Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 12/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2911519 | 0.88 | CHRM3 (0.43) | CHRM3CHRM2CHRM1MAPTUSP2 | |
| SCHEMBL2911294 | 0.86 | CHRM3 (0.45) | CHRM3MAPTRAB9ANPC1NPSR1 | |
| SCHEMBL975700 | 0.81 | KMT2A (0.55) | MAPTUSP2POLBTSHRHTT | |
| SCHEMBL1024112 | 0.77 | CHRM3 (0.40) | CHRM3MAPTRAB9ANPC1NPSR1 | |
| SCHEMBL26633143 | 0.75 | CHRM3 (0.48) | CHRM3CHRM2CHRM1MAPTRAB9A | |
| SCHEMBL1019446 | 0.74 | POLB (0.38) | CHRM3CHRM2CHRM1MAPTUSP2 | |
| SCHEMBL2905171 | 0.74 | CHRM3 (0.42) | CHRM3MAPTHTTRAB9ANPC1 | |
| SCHEMBL977943 | 0.73 | MAPT (0.46) | CHRM3MAPTUSP2POLBTSHR | |
| SCHEMBL17797001 | 0.73 | CHRM3 (0.52) | CHRM3CHRM2CHRM1MAPTUSP2 | |
| SCHEMBL4602252 | 0.72 | CHRM3 (0.51) | CHRM3CHRM2CHRM1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888545-B1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF SE (DE) | 2010-08-25 | — | — | EP | claimed |
| EP-1888545-A1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-20 | — | — | EP | claimed |
| WO-2006122933-A1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-23 | — | — | WO | claimed |
| EP-1888545-B1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF SE (DE) | 2010-08-25 | — | — | EP | disclosed |
| EP-1888545-A1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122933-A1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-23 | — | — | WO | disclosed |