Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 9/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906437 | 0.88 | CHRM3 (0.46) | CHRM3CHRM2CHRM1MAPTNPC1 | |
| SCHEMBL2905171 | 0.87 | CHRM3 (0.42) | CHRM3NTRK1MAPTNPC1RAB9A | |
| SCHEMBL4734232 | 0.83 | MAPT (0.41) | CHRM3NTRK1MAPTTACR1NPC1 | |
| SCHEMBL4733535 | 0.83 | MAPT (0.41) | CHRM3MAPTTACR1ALDH1A1 | |
| SCHEMBL977943 | 0.82 | MAPT (0.46) | CHRM3NTRK1MAPTNPC1RAB9A | |
| SCHEMBL4732975 | 0.82 | CA12 (0.44) | MAPTPOLBHTT | |
| SCHEMBL4730702 | 0.82 | MAPT (0.41) | CHRM3MAPTTACR1ALDH1A1 | |
| SCHEMBL4730073 | 0.81 | CA2 (0.39) | NPC1RAB9APOLBHTTALDH1A1 | |
| SCHEMBL4730301 | 0.81 | MAPT (0.40) | MAPTNPSR1POLBHTTHSD17B10 | |
| SCHEMBL3035362 | 0.78 | CHRM3 (0.46) | CHRM3CHRM2CHRM1NTRK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888545-B1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF SE (DE) | 2010-08-25 | — | — | EP | claimed |
| EP-1888545-A1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-20 | — | — | EP | claimed |
| WO-2006122933-A1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-23 | — | — | WO | claimed |
| EP-1888545-B1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF SE (DE) | 2010-08-25 | — | — | EP | disclosed |
| EP-1888545-A1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122933-A1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-23 | — | — | WO | disclosed |