Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 11/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905171 | 0.87 | CHRM3 (0.42) | CHRM3RAB9ANPC1NPSR1MEN1 | |
| SCHEMBL2906437 | 0.86 | CHRM3 (0.46) | CHRM3RAB9ANPC1NPSR1MEN1 | |
| SCHEMBL977511 | 0.81 | RAB9A (0.55) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL2911519 | 0.74 | CHRM3 (0.43) | CHRM3RAB9ANPC1NPSR1MAPT | |
| SCHEMBL978883 | 0.72 | MAPT (0.47) | CHRM3RAB9ANPC1MEN1KMT2A | |
| SCHEMBL4599192 | 0.72 | TSHR (0.44) | RAB9ANPC1NPSR1MEN1KMT2A | |
| SCHEMBL16438663 | 0.72 | CHRM3 (0.47) | CHRM3RAB9ANPC1NPSR1MEN1 | |
| SCHEMBL1024112 | 0.72 | CHRM3 (0.40) | CHRM3RAB9ANPC1NPSR1MEN1 | |
| SCHEMBL4602463 | 0.71 | NPC1 (0.47) | CHRM3RAB9ANPC1NPSR1MEN1 | |
| SCHEMBL2784708 | 0.70 | F2 (0.41) | RAB9ANPC1MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888545-B1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF SE (DE) | 2010-08-25 | — | — | EP | claimed |
| EP-1888545-A1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-20 | — | — | EP | claimed |
| WO-2006122933-A1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-23 | — | — | WO | claimed |
| EP-1888545-B1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF SE (DE) | 2010-08-25 | — | — | EP | disclosed |
| EP-1888545-A1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122933-A1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-23 | — | — | WO | disclosed |