SCHEMBL29064503

SCHEMBL29064503

SCSSc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.55
HPGD P15428 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MGLL Q99685 1/20 0.55
HSD17B10 Q99714 1/20 0.55
ALDH1A1 P00352 2/20 0.42
MAPK1 P28482 1/20 0.42
IDO1 P14902 1/20 0.38
FFAR1 O14842 1/20 0.34
MMP3 P08254 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29201828 0.74 HPGD (0.55) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL575878 0.74 SMN1; SMN2 (0.55) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL10700265 0.74 SMN1; SMN2 (0.55) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL776044 0.74 MAPT (0.55) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL5148 0.73 HPGD (1.00) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL7759264 0.73 HPGD (1.00) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL3880071 0.72
SCHEMBL576746 0.72 HSD17B10 (0.52) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL20150448 0.70 SMN1; SMN2 (0.50) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL9655918 0.70 MAPT (0.50) MAPTHPGDSMN1; SMN2MGLLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110643010-B Isocyanate composition and optical resin prepared from same 万华化学集团股份有限公司 2024-04-09 CN disclosed
CN-117801222-A Cyclohexane dimethylene diisocyanate composition, modified composition, polyurethane resin and optical resin 万华化学集团股份有限公司 2024-04-02 CN disclosed
CN-113980238-B Benzenedimethylene diisocyanate composition and preparation method and application thereof 万华化学集团股份有限公司 2024-02-27 CN disclosed
CN-114031744-B Bis (isocyanatomethyl) cyclohexane compositions, modified compositions thereof, and methods of making 万华化学集团股份有限公司 2023-12-19 CN disclosed
CN-116970144-A Xylylene diisocyanate composition and modified composition thereof, polyurethane resin and optical material 万华化学集团股份有限公司 2023-10-31 CN disclosed
CN-115073707-B Benzenedimethylene diisocyanate composition and preparation method and application thereof 万华化学集团股份有限公司 2023-09-26 CN disclosed
CN-116438214-A Sealing material for organic EL display element, cured product thereof, and organic EL display device 三井化学株式会社 2023-07-14 CN disclosed