Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | GSR | P00390 | 3/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29064680 | 0.96 | TXNRD1 (0.36) | TXNRD1MAPTGSRMERTKKDM4E | |
| SCHEMBL29064671 | 0.87 | TXNRD1 (0.38) | TXNRD1MAPTGSRHTT | |
| SCHEMBL16470410 | 0.86 | MAPT (0.44) | TXNRD1MAPTGSRMERTKKDM4E | |
| SCHEMBL16470439 | 0.84 | TXNRD1 (0.36) | TXNRD1MAPTGSRMERTKPIN1 | |
| SCHEMBL29064667 | 0.83 | TXNRD1 (0.41) | TXNRD1MAPTKDM4EMEN1LMNA | |
| SCHEMBL29064672 | 0.82 | TXNRD1 (0.37) | TXNRD1MAPTGSRMERTKKDM4E | |
| SCHEMBL29064683 | 0.81 | TXNRD1 (0.42) | TXNRD1MAPTGSR | |
| SCHEMBL29064677 | 0.77 | KDM4E (0.34) | KDM4EKMT2A | |
| SCHEMBL29064684 | 0.77 | TXNRD1 (0.30) | TXNRD1 | |
| SCHEMBL16470287 | 0.76 | MAPT (0.41) | TXNRD1MAPTKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116265460-A | Thiazole methyl pyridine amine compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | disclosed |