Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 4/20 | 0.37 |
| ▸ | GSR | P00390 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16469858 | 0.91 | MAPT (0.42) | TXNRD1GSRMAPTALDH1A1MAPK1 | |
| SCHEMBL16470360 | 0.89 | TXNRD1 (0.37) | TXNRD1GSRMAPTALDH1A1MAPK1 | |
| SCHEMBL29064664 | 0.87 | TXNRD1 (0.39) | TXNRD1MAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL29064680 | 0.86 | TXNRD1 (0.36) | TXNRD1GSRMAPTL3MBTL1MERTK | |
| SCHEMBL29064660 | 0.86 | TXNRD1 (0.43) | TXNRD1GSRMAPTMAPK1 | |
| SCHEMBL29064687 | 0.85 | TXNRD1 (0.39) | TXNRD1GSRMAPTMAPK1HTT | |
| SCHEMBL29064685 | 0.82 | TXNRD1 (0.34) | TXNRD1GSRMAPTMERTKFGFR4 | |
| SCHEMBL29064665 | 0.81 | ALDH1A1 (0.35) | TXNRD1MAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL29064682 | 0.81 | ALDH1A1 (0.31) | TXNRD1MAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL16470365 | 0.80 | MAPT (0.39) | TXNRD1MAPTALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116265460-B | Thiazole methyl pyridine amine compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-116265460-A | Thiazole methyl pyridine amine compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | claimed |
| CN-116265460-B | Thiazole methyl pyridine amine compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-116265460-A | Thiazole methyl pyridine amine compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | disclosed |