Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.54 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29064867 | 1.00 | GRIA1 (0.54) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL8910894 | 0.77 | PARP1 (0.47) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL29064845 | 0.77 | GRIA1 (0.41) | GRIA1GRIA2GRIA3GRIA4ADORA3 | |
| SCHEMBL8558924 | 0.72 | MEN1 (0.49) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL9094035 | 0.71 | GRIA1 (0.53) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL28823746 | 0.67 | GRIA1 (0.52) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL24590158 | 0.67 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL9092540 | 0.67 | GRIA1 (0.52) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL26352125 | 0.66 | GRIA1 (0.51) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL9093084 | 0.66 | GRIA1 (0.51) | GRIA1GRIA2GRIA3GRIA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528867-A | Compounds for the treatment of Alzheimer's disease | 艾伯塔大学理事会 | 2023-08-01 | — | — | CN | disclosed |