Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29064867 | 0.77 | GRIA1 (0.54) | GRIA1GRIA2GRIA3GRIA4ADORA3 | |
| SCHEMBL29064868 | 0.77 | GRIA1 (0.54) | GRIA1GRIA2GRIA3GRIA4ADORA3 | |
| SCHEMBL9256291 | 0.71 | EPHX2 (0.43) | ATM | |
| SCHEMBL9256288 | 0.71 | EPHX2 (0.43) | ATM | |
| SCHEMBL27349103 | 0.70 | PPARA (0.48) | GRIA1GRIA2GRIA3GRIA4IDO1 | |
| SCHEMBL7551469 | 0.69 | POLB (0.49) | IDO1CTSSCTSKATM | |
| SCHEMBL24335161 | 0.68 | TLR2 (0.41) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL13342905 | 0.68 | PPARA (0.46) | IDO1PPARAPPARGCTSSCTSK | |
| SCHEMBL58394 | 0.68 | CTSS (0.49) | IDO1PPARAPPARGCTSSCTSK | |
| SCHEMBL5024738 | 0.68 | CTSS (0.49) | IDO1PPARAPPARGCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528867-A | Compounds for the treatment of Alzheimer's disease | 艾伯塔大学理事会 | 2023-08-01 | — | — | CN | disclosed |