Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 6/20 | 0.47 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24359424 | 0.83 | MKNK1 (0.39) | CYP11B1CYP11B2 | |
| SCHEMBL29064869 | 0.80 | MKNK1 (0.43) | ABCB1ABCC1CYP11B1CYP11B2 | |
| SCHEMBL24335577 | 0.78 | NAMPT (0.41) | ABCB1ABCC1 | |
| SCHEMBL21878179 | 0.77 | HTT (0.45) | POLBTP53MAPT | |
| SCHEMBL1980974 | 0.76 | ABCB1 (0.55) | ABCB1ABCC1POLBTP53CYP11B1 | |
| SCHEMBL29064835 | 0.75 | LMNA (0.47) | POLBMAPT | |
| SCHEMBL17743341 | 0.73 | KAT2B (0.47) | POLBMAPT | |
| SCHEMBL28296826 | 0.73 | CYP1A2 (0.57) | POLBMAPT | |
| SCHEMBL6370287 | 0.73 | MAPT (0.58) | MAPT | |
| SCHEMBL1514945 | 0.73 | KAT2B (0.44) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232438-A1 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | The Governors of the University of Alberta (CA) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022082305-A1 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2022-04-28 | — | — | WO | disclosed |