Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 8/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29065081 | 0.86 | ALDH1A1 (0.36) | KDM4EELANEMEN1KMT2AALDH1A1 | |
| SCHEMBL29064939 | 0.81 | PRNP (0.37) | KDM4ERXFP1TSHRMEN1KMT2A | |
| SCHEMBL29065057 | 0.80 | AOC2 (0.34) | KDM4EF10MEN1KMT2AALDH1A1 | |
| SCHEMBL22042092 | 0.80 | KDM4E (0.50) | KDM4ENPSR1RXFP1TSHRF10 | |
| SCHEMBL29065058 | 0.79 | MEN1 (0.31) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL17327071 | 0.79 | KDM4E (0.44) | KDM4ENPSR1RXFP1NOD2NOD1 | |
| SCHEMBL29065165 | 0.78 | CDC7 (0.44) | KDM4ENPSR1RXFP1ELANETSHR | |
| SCHEMBL24036358 | 0.76 | F10 (0.45) | KDM4ENPSR1RXFP1NOD2NOD1 | |
| SCHEMBL29065006 | 0.76 | MAPT (0.34) | RXFP1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29065117 | 0.76 | MAPT (0.33) | F10MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710430-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2023-09-05 | — | — | CN | disclosed |