Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29064951 | 0.85 | — | — | |
| SCHEMBL29065150 | 0.85 | GLS (0.30) | — | |
| SCHEMBL29065165 | 0.80 | CDC7 (0.44) | MAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL29065083 | 0.79 | POLB (0.35) | ALDH1A1 | |
| SCHEMBL29065043 | 0.79 | CYP1B1 (0.38) | MAPT | |
| SCHEMBL29064958 | 0.77 | CYP2D6 (0.33) | — | |
| SCHEMBL29065003 | 0.77 | FFAR1 (0.33) | MAPT | |
| SCHEMBL29064928 | 0.75 | — | — | |
| SCHEMBL28457543 | 0.68 | KDM4E (0.39) | MAPTKDM4EL3MBTL1ALDH1A1ALOX12 | |
| SCHEMBL24036055 | 0.67 | SRC (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710430-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2023-09-05 | — | — | CN | disclosed |