Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 7/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29065110 | 0.85 | NOTUM (0.34) | CNR2 | |
| SCHEMBL29064958 | 0.83 | CYP2D6 (0.33) | FFAR1CNR2 | |
| SCHEMBL29065052 | 0.80 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL29065022 | 0.80 | CYP2D6 (0.39) | MAPTMEN1TSHRKMT2ATP53 | |
| SCHEMBL29065040 | 0.80 | SLC5A7 (0.33) | MAPTTSHRSMN1; SMN2TP53 | |
| SCHEMBL29065077 | 0.77 | MAPT (0.33) | MAPT | |
| SCHEMBL29065150 | 0.77 | GLS (0.30) | — | |
| SCHEMBL29184884 | 0.77 | CHRM3 (0.32) | MAPTTP53 | |
| SCHEMBL29065117 | 0.69 | MAPT (0.33) | MAPTMEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL29065057 | 0.67 | AOC2 (0.34) | MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710430-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2023-09-05 | — | — | CN | disclosed |