Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24035966 | 0.86 | MAPT (0.38) | MAPTKMT2ATHRBTSHRHTT | |
| SCHEMBL24852874 | 0.86 | MAPT (0.37) | MAPTKMT2ATHRBMEN1LMNA | |
| SCHEMBL29065017 | 0.84 | CNR1 (0.32) | MAPTKMT2ATHRBTSHR | |
| SCHEMBL29065076 | 0.84 | MAPT (0.38) | MAPTKMT2ATHRBMEN1LMNA | |
| SCHEMBL29064987 | 0.83 | IRAK4 (0.32) | MAPTKMT2ATHRBMEN1LMNA | |
| SCHEMBL29064936 | 0.82 | MAPT (0.35) | MAPTKMT2ATHRBMEN1LMNA | |
| SCHEMBL29065134 | 0.82 | LMNA (0.36) | MAPTKMT2AMEN1LMNATP53 | |
| SCHEMBL29184877 | 0.81 | SLC5A7 (0.31) | — | |
| SCHEMBL29065105 | 0.81 | SLC5A7 (0.31) | — | |
| SCHEMBL29065021 | 0.81 | SLC5A7 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710430-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2023-09-05 | — | — | CN | disclosed |