Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29064981 | 0.87 | MAPT (0.39) | LMNAMAPTMEN1KMT2ATP53 | |
| SCHEMBL29065062 | 0.85 | CNR1 (0.34) | LMNAMAPTMEN1KMT2ATP53 | |
| SCHEMBL29065032 | 0.85 | CNR1 (0.38) | LMNATP53CNR1 | |
| SCHEMBL24035319 | 0.83 | HDAC1 (0.38) | LMNAMAPTMEN1KMT2ATP53 | |
| SCHEMBL29065124 | 0.82 | MAPT (0.36) | LMNAMAPTMEN1KMT2ATP53 | |
| SCHEMBL24036171 | 0.80 | HDAC1 (0.41) | LMNAMAPTMEN1KMT2ATP53 | |
| SCHEMBL29065076 | 0.78 | MAPT (0.38) | LMNAMAPTMEN1KMT2ATP53 | |
| SCHEMBL29064936 | 0.76 | MAPT (0.35) | LMNAMAPTMEN1KMT2ATP53 | |
| SCHEMBL29065022 | 0.73 | CYP2D6 (0.39) | LMNAMAPTMEN1KMT2ATP53 | |
| SCHEMBL30295646 | 0.71 | MAPT (0.39) | LMNAMAPTCNR1HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710430-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2023-09-05 | — | — | CN | disclosed |