Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24036136 | 0.85 | MAOA (0.44) | ALDH1A1KDM4EACHEGAASMN1; SMN2 | |
| SCHEMBL1421925 | 0.82 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1KDM4EPLA2G4AACHE | |
| SCHEMBL9305705 | 0.80 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1KDM4EPLA2G4AACHE | |
| SCHEMBL13999769 | 0.79 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1KDM4EPLA2G4AACHE | |
| SCHEMBL13999768 | 0.76 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1KDM4EPLA2G4AACHE | |
| SCHEMBL2517764 | 0.75 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1KDM4EPLA2G4AACHE | |
| SCHEMBL27805949 | 0.74 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1KDM4EPLA2G4AACHE | |
| SCHEMBL287556 | 0.74 | KDM4E (0.47) | L3MBTL1ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL3557689 | 0.73 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1KDM4EPLA2G4AACHE | |
| SCHEMBL578096 | 0.73 | KDM4E (0.46) | L3MBTL1ALDH1A1KDM4EGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710430-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2023-09-05 | — | — | CN | disclosed |