Dl-Phenylalanine

Dl-Phenylalanine

SCHEMBL29065229

CC(C)(C)OC(=O)NCC(=O)O.NC(Cc1ccccc1)C(=O)O.O=C1CCC(=O)N1O

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.46
PKM P14618 2/20 0.45
ALPI P09923 1/20 0.45
PTGS1 P23219 1/20 0.45
XIAP P98170 1/20 0.45
SIGMAR1 Q99720 1/20 0.42
CTSS P25774 2/20 0.41
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
CTSK P43235 1/20 0.41
AKT1 P31749 1/20 0.41
ATM Q13315 1/20 0.40
ACE P12821 1/20 0.40
NPFFR1 Q9GZQ6 1/20 0.39
NPFFR2 Q9Y5X5 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
APP P05067 1/20 0.39
SYK P43405 1/20 0.39
SCN9A Q15858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Phenylalanine SCHEMBL29065230 0.89 SLC7A5 (0.56) SLC7A5PKMALPIPTGS1XIAP
SCHEMBL2083155 0.82 L3MBTL1 (0.40) SIGMAR1NPFFR1NPFFR2ALDH1A1
Dl-Phenylalanine SCHEMBL27582268 0.81 SLC7A5 (0.69) SLC7A5PKMALPIPTGS1XIAP
SCHEMBL8661715 0.78 ACE (0.64) CTSSCTSLCTSBCTSKAKT1
SCHEMBL20038756 0.76 SLC7A5 (0.52) SLC7A5PKMALPIPTGS1XIAP
SCHEMBL12463672 0.76 SLC7A5 (0.52) SLC7A5PKMALPIPTGS1XIAP
SCHEMBL12463287 0.76 SLC7A5 (0.52) SLC7A5PKMALPIPTGS1XIAP
SCHEMBL19143295 0.74 SLC7A5 (0.64) SLC7A5PKMALPIPTGS1XIAP
SCHEMBL12645129 0.74 SLC7A5 (0.64) SLC7A5PKMALPIPTGS1XIAP
SCHEMBL2174856 0.74 ACE (0.67) CTSSCTSLCTSBCTSKAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116640182-A Transdermal delivery system for polypeptides and related compounds 泰飞尔生物医药(苏州)有限公司 2023-08-25 CN disclosed