SCHEMBL2083155

SCHEMBL2083155

CC(C)(C)OC(=O)NCC(=O)O.O=C1CCC(=O)N1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.40
SIGMAR1 Q99720 1/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
GAA P10253 2/20 0.39
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
KDM4E B2RXH2 2/20 0.38
LMNA P02545 2/20 0.38
TDP1 Q9NUW8 1/20 0.37
GFER P55789 1/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
NPFFR1 Q9GZQ6 1/20 0.36
NPFFR2 Q9Y5X5 1/20 0.36
GLA P06280 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
CASP1 P29466 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Phenylalanine SCHEMBL29065229 0.82 SLC7A5 (0.46) SIGMAR1ALDH1A1NPFFR1NPFFR2
SCHEMBL17906 0.82 MEN1 (0.52) KMT2AMEN1GAAALDH1A1TSHR
Cyclopentane SCHEMBL8727534 0.80 EPHX1 (0.49) L3MBTL1SIGMAR1KMT2AMEN1GAA
Succinimide SCHEMBL6525020 0.80 DDB1 (0.41) L3MBTL1SIGMAR1KMT2AMEN1GAA
Methane SCHEMBL1486197 0.80 MEN1 (0.50) KMT2AMEN1GAAALDH1A1TSHR
SCHEMBL6603412 0.80 MEN1 (0.50) KMT2AMEN1GAAALDH1A1TSHR
Hydrochloric Acid SCHEMBL77819 0.80 MEN1 (0.50) KMT2AMEN1GAAALDH1A1TSHR
SCHEMBL6679504 0.80 MEN1 (0.50) KMT2AMEN1GAAALDH1A1TSHR
Bicarbonate SCHEMBL28028118 0.80 MEN1 (0.50) KMT2AMEN1GAAALDH1A1TSHR
SCHEMBL9464092 0.80 MEN1 (0.50) KMT2AMEN1GAAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748843-A2 ANTIBODY-DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Medilink Therapeutics (Suzhou) Co., Ltd. (CN) 2026-05-27 EP disclosed
EP-4556026-A1 ANTIBODY-DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Medilink Therapeutics (Suzhou) Co., Ltd. (CN) 2025-05-21 EP disclosed
EP-4552654-A1 ANTIBODY-DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Medilink Therapeutics (Suzhou) Co., Ltd. (CN) 2025-05-14 EP disclosed
US-7863304-B2 Analogs of glycyl-prolyl-glutamate NEUREN PHARMACEUTICALS LIMITED (NZ) 2011-01-04 US disclosed
US-20080145335-A1 Analogs of Glycyl-Prolyl-Glutamate NEUREN PHARMACEUTICALS LIMITED (NZ) 2008-06-19 US disclosed
US-7081481-B2 Excitatory amino acid receptor modulators ELI LILLY AND COMPANY (US) 2006-07-25 US disclosed
EP-1189874-B1 EXCITATORY AMINO ACID RECEPTOR MODULATORS LILLY SA (ES) 2005-01-26 EP disclosed
US-20040102521-A1 Excitatory amino acid receptor modulators ELI LILLY AND COMPANY 2004-05-27 US disclosed
US-6504052-B1 2-carboxycyclopropyl glycine derivatives, used as agonists of glutamate receptors for prophylaxis of psychological and nervous system disorders; anxiolytics; antidepressants; drug abuse; anticonvulsant, analgesic and antiemetic agents ELI LILLY AND COMPANY 2003-01-07 US disclosed
US-6498180-B1 SUCH AS 2-(3'-HYDROXYMETHYL-2'-CARBOXYCYCLOPROPYL)GLYCINE; MODULATING METABOTROPIC GLUTAMATE RECEPTOR; TREATING DISORDERS OF CENTRAL NERVOUS ELI LILLY AND COMPANY 2002-12-24 US disclosed
CN-1152914-A Technetium-sulphonamide complexes, their use, pharmaceutical agents containing them, and process for producing the complexes and agents SCHERING AG (DE) 1997-06-25 CN disclosed
EP-0498680-A1 New beta-amino-alpha-hydroxycarboxylic acids and their use Sankyo Company Limited (JP) 1992-08-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040102521-A1 Excitatory amino acid receptor modulators GRM1, GRM2, GRIN1 L3MBTL1 2983/4885SIGMAR1 167/4885KMT2A 1257/4885
US-20080145335-A1 Analogs of Glycyl-Prolyl-Glutamate GLS, GLUL, HIF1A L3MBTL1 497/4885SIGMAR1 2873/4885KMT2A 1461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.