Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743832 | 1.00 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAAHDAC1HDAC7 | |
| SCHEMBL5691047 | 0.83 | CYP2C9 (0.50) | ALDH1A1HDAC1HDAC6ARKMT2A | |
| SCHEMBL29519711 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL5086660 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL7170373 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KDM4EGAAHDAC1HDAC7 | |
| Benzene SCHEMBL11307346 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL1988094 | 0.76 | UGT2B7 (0.47) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL977301 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KDM4EHDAC1HDAC7HDAC8 | |
| SCHEMBL27994673 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAAHDAC1HDAC7 | |
| SCHEMBL2482183 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KDM4EHDAC1HDAC7HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991940-B1 | USE OF MONOLITHIC SORBENTS FOR PREPARATIVE CHROMATOGRAPHIC SEPARATION | MERCK PATENT GMBH (DE) | 2010-08-25 | — | — | EP | disclosed |
| US-6398962-B1 | DISSOLVING A WATER-SOLUBLE POLYMER OR PORE FORMING AGENT AND A MATRIX AGENT IN A MEDIUM THAT PROMOTES THE HYDROLYSIS OF METALORGANIC COMPOUNDS TO FORM SILICON OXIDE SHAPED BODIES; SOLIDIFICATION AND ROASTING; FLUID FLOW | MERCK KGAA (DE) | 2002-06-04 | — | — | US | disclosed |
| EP-0991940-A1 | USE OF MONOLITHIC SORBENTS FOR PREPARATIVE CHROMATOGRAPHIC SEPARATION | MERCK PATENT GmbH (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998058253-A1 | USE OF MONOLITHIC SORBENTS FOR PREPARATIVE CHROMATOGRAPHIC SEPARATION | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | WO | disclosed |
| US-4988458-A | Liquid crystal phase containing admixtures which effect temperature compensation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| US-4914196-A | CHIRAL REACTANTS FOR ALDEHYDES, KETONES, N-SUBSTITUTED IMINES | CIBA-GEIGY CORPORATION (US) | 1990-04-03 | — | — | US | disclosed |
| US-4826965-A | Metal complexes containing optically active sugar ligands, a process for their preparation and their use as chiral reactants for synthesis of alcohols and amines | CIBA-GEIGY CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |