SCHEMBL2482183

SCHEMBL2482183

OC(c1c2ccccc2cc2ccccc12)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
HSD17B10 Q99714 2/20 0.39
CYP1A2 P05177 2/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
GLA P06280 1/20 0.39
CYP2C19 P33261 1/20 0.39
TRPM4 Q8TD43 1/20 0.38
PTPN1 P18031 1/20 0.38
HIF1A Q16665 1/20 0.37
CYP1B1 Q16678 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
HTR2A P28223 1/20 0.36
NQO2 P16083 1/20 0.36
DHODH Q02127 1/20 0.36
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3075110 1.00 ALDH1A1 (0.39) ALDH1A1MEN1KMT2AHSD17B10CYP1A2
SCHEMBL977301 1.00 ALDH1A1 (0.39) ALDH1A1MEN1KMT2AHSD17B10CYP1A2
SCHEMBL8745296 0.87 ALDH1A1 (0.36) ALDH1A1MEN1KMT2AHSD17B10CYP1A2
SCHEMBL14155951 0.85 MEN1 (0.37) ALDH1A1MEN1KMT2AHSD17B10CYP1A2
SCHEMBL7074543 0.79 PTPN22 (0.47) ALDH1A1MEN1KMT2AHSD17B10CYP1A2
SCHEMBL29946603 0.79 PTPN22 (0.47) ALDH1A1MEN1KMT2AHSD17B10CYP1A2
SCHEMBL27925964 0.79 L3MBTL1 (0.37) ALDH1A1MEN1KMT2AHSD17B10CYP1A2
SCHEMBL14294943 0.78 DHODH (0.32) PTPN1DHODH
SCHEMBL10132729 0.78 DHODH (0.32) PTPN1DHODH
SCHEMBL488964 0.76 ALDH1A1 (0.46) ALDH1A1MEN1KMT2AHSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 329 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760750-B1 Process for preparing levoketoconazole NURAY CHEMICALS PRIVATE LIMITED (IN) 2023-09-19 US claimed
CN-110407984-A A kind of viscosity reduction fluorescent type poly carboxylic acid series water reducer and preparation method thereof JIANGSU ARIT NEW MAT CO LTD 2019-11-05 CN claimed
US-9334253-B2 Direct trifluoromethylations using trifluoromethane UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2016-05-10 US claimed
CN-103649263-A Direct trifluoromethylation using trifluoromethane UNIV SOUTHERN CALIFORNIA 2014-03-19 CN claimed
WO-2012148772-A1 DIRECT TRIFLUOROMETHYLATIONS USING TRIFLUOROMETHANE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2012-11-01 WO claimed
CN-1269793-C Process for producing 3, 3-diarylpropylamines SANOL ARZNEI SCHWARZ GMBH (DE) 2006-08-16 CN claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
CN-1441771-A Process for producing 3, 3-diarylpropylamines SANOL ARZNEI SCHWARZ GMBH (DE) 2003-09-10 CN claimed
US-6346194-B1 SEPARATING RACEMIC MIXTURE BY CONTACTING WITH CHIRAL STATIONARY PHASE CONSISTING OF YOHIMBINE OR ANALOG THEREOF COVALENTLY BOUND TO REFRACTORY INORGANIC OXIDE CARRIER VIA SPACER UOP LLC 2002-02-12 US claimed
US-20250228873-A1 C25 R AND S ISOMERS OF AMINOSTEROLS AND METHODS OF MAKING AND USING THE SAME ENTERIN, INC. (US) 2025-07-17 US disclosed
US-20250002527-A1 STEROID COMPOUND AND CONJUGATE THEREOF DUALITY BIOLOGICS (SHANGHAI) CO., LTD. (CN) 2025-01-02 US disclosed
EP-4469466-A1 C25 R AND S ISOMERS OF AMINOSTEROLS AND METHODS OF MAKING AND USING THE SAME Enterin, Inc. (US) 2024-12-04 EP disclosed
CN-116196909-B Silica gel @ polyaniline @ polysaccharide derivative core-shell CSP filler and preparation method and application thereof 昆明医科大学 2024-07-16 CN disclosed
WO-2023173359-A1 METABOLIC DISEASE THERAPEUTIC AGENT OR PREVENTIVE AGENT 北京大学 2023-09-21 WO disclosed
EP-0281951-A1 Alkyl-phenylcarbamate derivative of polysaccharide DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1988-09-14 EP disclosed
EP-0254685-A2 Complexes with optically active sugar ligands, process for their preparation and their use CIBA-GEIGY AG (CH) 1988-01-27 EP disclosed
US-4701569-A PERFLUOROALKYLATION OF CARBONYL COMPOUNDS IN PRESENCE OF ZINC IN ABSENCE OF ULTRASONIC WAVES RHONE-POULENC SPECIALTIES CHIMIQUES (FR) 1987-10-20 US disclosed
US-4687863-A Optically active hydroxyiodolactone NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1987-08-18 US disclosed
EP-0137794-A1 CLAVAM DERIVATIVES BEECHAM GROUP PLC (GB) 1985-04-24 EP disclosed
WO-1984003282-A1 CLAVAM DERIVATIVES BEECHAM GROUP PLC (GB) 1984-08-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250228873-A1 C25 R AND S ISOMERS OF AMINOSTEROLS AND METHODS OF MAKING AND USING THE SAME DHCR7, HSD17B7, HSD3B1 ALDH1A1 2408/4885MEN1 432/4885KMT2A 4197/4885
US-20250002527-A1 STEROID COMPOUND AND CONJUGATE THEREOF CYP17A1, CYP21A2, HSD17B7 ALDH1A1 1986/4885MEN1 52/4885KMT2A 2476/4885
US-11760750-B1 Process for preparing levoketoconazole KHK, KYAT3, PLK3 ALDH1A1 2659/4885MEN1 2073/4885KMT2A 1550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.