Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.72 |
| ▸ | GAA | P10253 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | BCL2 | P10415 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28738320 | 0.91 | ALDH1A1 (0.68) | ALDH1A1GAACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29065799 | 0.90 | ALDH1A1 (0.73) | ALDH1A1GAACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29065795 | 0.89 | ALDH1A1 (0.64) | ALDH1A1GAACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28738360 | 0.86 | ALDH1A1 (0.62) | ALDH1A1GAACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29065794 | 0.84 | KMT2A (0.55) | ALDH1A1GAACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28738377 | 0.81 | CASR (0.55) | ALDH1A1GAACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29065791 | 0.78 | MAPT (0.55) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL28738301 | 0.77 | MAPT (0.54) | ALDH1A1GAACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29065793 | 0.77 | CASR (0.57) | ALDH1A1MEN1KMT2ASMN1; SMN2RECQL | |
| SCHEMBL28008951 | 0.74 | ALDH1A1 (1.00) | ALDH1A1GAACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230526-B | Synthesis method of 4-3 (H) quinazolinone and derivative thereof | 重庆医科大学 | 2023-06-23 | — | — | CN | claimed |
| CN-114230526-B | Synthesis method of 4-3 (H) quinazolinone and derivative thereof | 重庆医科大学 | 2023-06-23 | — | — | CN | disclosed |