Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NRP1 | O14786 | 6/20 | 0.60 |
| ▸ | NPR1 | P16066 | 1/20 | 0.60 |
| ▸ | CCKAR | P32238 | 12/20 | 0.39 |
| ▸ | CCKBR | P32239 | 11/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30679285 | 0.90 | NRP1 (0.70) | NRP1NPR1CCKARCCKBR | |
| SCHEMBL4569813 | 0.88 | NRP1 (0.76) | NRP1NPR1CCKARCCKBR | |
| SCHEMBL4572338 | 0.86 | NRP1 (0.65) | NRP1NPR1CCKARCCKBRATM | |
| SCHEMBL4572299 | 0.78 | NRP1 (0.77) | NRP1NPR1CCKARCCKBRATM | |
| Trifluoroacetic Acid SCHEMBL29655756 | 0.78 | NRP1 (0.50) | NRP1NPR1CCKARCCKBRLMNA | |
| SCHEMBL4569831 | 0.77 | NRP1 (0.77) | NRP1NPR1 | |
| SCHEMBL4572336 | 0.76 | NRP1 (0.72) | NRP1NPR1CCKARCCKBRATM | |
| SCHEMBL4569863 | 0.76 | NRP1 (0.58) | NRP1NPR1CCKARCCKBRATM | |
| SCHEMBL29655722 | 0.76 | NRP1 (0.52) | NRP1NPR1CCKARCCKBRLMNA | |
| SCHEMBL4572326 | 0.75 | NRP1 (0.59) | NRP1NPR1CCKARCCKBRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117414430-A | Application of EPCR pathway activator in preparation of anti-fibrosis agent | 四川大学华西第二医院 | 2024-01-19 | — | — | CN | disclosed |
| CN-113952456-B | Application of EPCR pathway activator in preparation of anti-fibrosis agent | 四川大学华西第二医院 | 2023-12-15 | — | — | CN | disclosed |
| CN-114452389-B | Anti-fibrosis pharmaceutical composition and application thereof | 四川大学华西第二医院 | 2023-08-25 | — | — | CN | disclosed |