Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NRP1 | O14786 | 1/20 | 0.52 |
| ▸ | NPR1 | P16066 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CCKBR | P32239 | 4/20 | 0.45 |
| ▸ | CCKAR | P32238 | 4/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 2/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29655756 | 0.97 | NRP1 (0.50) | NRP1NPR1L3MBTL1ATMCCKBR | |
| SCHEMBL4569813 | 0.81 | NRP1 (0.76) | NRP1NPR1CCKBRCCKAR | |
| Trifluoroacetic Acid SCHEMBL30679285 | 0.81 | NRP1 (0.70) | NRP1NPR1CCKBRCCKAR | |
| SCHEMBL4572338 | 0.78 | NRP1 (0.65) | NRP1NPR1L3MBTL1ATMCCKBR | |
| SCHEMBL29066366 | 0.76 | NRP1 (0.60) | NRP1NPR1L3MBTL1ATMCCKBR | |
| SCHEMBL4572336 | 0.71 | NRP1 (0.72) | NRP1NPR1L3MBTL1ATMCCKBR | |
| SCHEMBL4569863 | 0.71 | NRP1 (0.58) | NRP1NPR1L3MBTL1ATMCCKBR | |
| SCHEMBL13552626 | 0.70 | L3MBTL1 (0.55) | NRP1NPR1L3MBTL1ATMCCKBR | |
| SCHEMBL4572299 | 0.70 | NRP1 (0.77) | NRP1NPR1L3MBTL1ATMCCKBR | |
| SCHEMBL4569831 | 0.69 | NRP1 (0.77) | NRP1NPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117414430-A | Application of EPCR pathway activator in preparation of anti-fibrosis agent | 四川大学华西第二医院 | 2024-01-19 | — | — | CN | disclosed |
| CN-113952456-B | Application of EPCR pathway activator in preparation of anti-fibrosis agent | 四川大学华西第二医院 | 2023-12-15 | — | — | CN | disclosed |
| CN-114452389-B | Anti-fibrosis pharmaceutical composition and application thereof | 四川大学华西第二医院 | 2023-08-25 | — | — | CN | disclosed |
| WO-2022127654-A1 | ANTI-FIBROSIS PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 四川大学华西第二医院 | 2022-06-23 | — | — | WO | disclosed |