SCHEMBL29066468

SCHEMBL29066468

CC(C)CC(O)Cc1ccccc1.CC(CCO)CCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 4/20 0.44
SIGMAR1 Q99720 3/20 0.40
SLC6A2 P23975 2/20 0.40
TAAR1 Q96RJ0 2/20 0.40
MAOA P21397 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
CYP2A6 P11509 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
KDM4E B2RXH2 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
TSHR P16473 1/20 0.38
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112994 0.84 TDP1 (0.54) TRPA1SIGMAR1SLC6A2TAAR1MAOA
SCHEMBL27498397 0.84 TDP1 (0.54) TRPA1SIGMAR1SLC6A2TAAR1MAOA
SCHEMBL26606263 0.84 TDP1 (0.54) TRPA1SIGMAR1SLC6A2TAAR1MAOA
SCHEMBL28008217 0.82 TDP1 (0.52) TRPA1SIGMAR1SLC6A2TAAR1MAOA
SCHEMBL7523892 0.82 TRPA1 (0.52) TRPA1SIGMAR1SLC6A2TAAR1MAOA
SCHEMBL105502 0.82 TRPA1 (0.52) TRPA1SIGMAR1SLC6A2TAAR1MAOA
SCHEMBL7527686 0.82 TRPA1 (0.52) TRPA1SIGMAR1SLC6A2TAAR1MAOA
SCHEMBL29066465 0.81 TRPA1 (0.45) TRPA1SIGMAR1SLC6A2SLC6A3MEN1
Fluoride SCHEMBL28017588 0.81 TRPA1 (0.50) TRPA1SIGMAR1SLC6A2TAAR1MAOA
SCHEMBL109763 0.79 TSHR (0.47) SLC6A2SLC6A4SLC6A3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115427421-A 3' -ketoside compounds with slow release of volatile alcohols 格莱克科学有限公司 2022-12-02 CN claimed
CN-115427421-A 3' -ketoside compounds with slow release of volatile alcohols 格莱克科学有限公司 2022-12-02 CN disclosed