Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523892 | 1.00 | TRPA1 (0.52) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL105502 | 1.00 | TRPA1 (0.52) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| Fluoride SCHEMBL28017588 | 0.98 | TRPA1 (0.50) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL3091848 | 0.86 | TRPA1 (0.52) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL3091836 | 0.86 | TRPA1 (0.52) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL19739052 | 0.83 | TRPA1 (0.48) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL21703616 | 0.83 | TRPA1 (0.48) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL29066468 | 0.82 | TRPA1 (0.44) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL110013 | 0.82 | TRPA1 (0.56) | TRPA1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL1833635 | 0.81 | TRPA1 (0.55) | TRPA1TAAR1SLC6A2SIGMAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094753-A1 | OPTICALLY ACTIVE BENZYLALKYLCARBINOLS, THEIR PREPARATION AN D USE IN PERFUMERY | RHODIA CHIREX, INC. (US) | 2002-11-28 | — | — | WO | claimed |
| US-20020177738-A1 | Novel optically active benzylalkylcarbinols, their preparation and use | RHODIA CHIREX INC. | 2002-11-28 | — | — | US | claimed |
| US-20020119909-A1 | Preparation of enantiomerically enriched flavor and fragrance components | RHODIA CHIREX, INC. | 2002-08-29 | — | — | US | claimed |
| US-11787813-B2 | Substituted pyrazolopyrimidines and substituted purines and their use as ubiquitin-specific-processing protease 1 (USP1) inhibitors | KSQ Therapeutics, Inc. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230219965-A1 | NITROGEN-CONTAINING FUSED BICYCLIC COMPOUNDS AND THEIR USE AS UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 1 (USP1) INHIBITORS | KSQ Therapeutics, Inc. | 2023-07-13 | — | — | US | disclosed |
| US-20230203046-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AND SUBSTITUTED PURINES AND THEIR USE AS UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 1 (USP1) INHIBITORS | KSQ Therapeutics, Inc. | 2023-06-29 | — | — | US | disclosed |
| US-10428029-B2 | Isoxazole carboxamide compounds | Epizyme, Inc. (US) | 2019-10-01 | — | — | US | disclosed |
| US-20170362217-A1 | Substituted Piperidine Compounds | Epizyme, Inc. (US) | 2017-12-21 | — | — | US | disclosed |
| US-20170362191-A1 | Substituted Cyclohexylamine Compounds | Epizyme, Inc. (US) | 2017-12-21 | — | — | US | disclosed |
| US-20170355695-A1 | SMYD Inhibitors | Epizyme, Inc. (US) | 2017-12-14 | — | — | US | disclosed |
| US-20170253601-A1 | Substituted Pyrrolidine Compounds | Epizyme, Inc. (US) | 2017-09-07 | — | — | US | disclosed |
| US-20170247326-A1 | Substituted Pyrrolidine Carboxamide Compounds | Epizyme, Inc. (US) | 2017-08-31 | — | — | US | disclosed |
| US-20170247326-A1 | Substituted Pyrrolidine Carboxamide Compounds | Epizyme, Inc. (US) | 2017-08-31 | — | — | US | disclosed |
| US-20170190676-A1 | Isoxazole Carboxamide Compounds | Epizyme, Inc. (US) | 2017-07-06 | — | — | US | disclosed |
| US-20170190676-A1 | Isoxazole Carboxamide Compounds | Epizyme, Inc. (US) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787813-B2 | Substituted pyrazolopyrimidines and substituted purines and their use as ubiquitin-specific-processing protease 1 (USP1) inhibitors | USP1, UPP1, USP2 | TRPA1 4618/4885TAAR1 3135/4885SLC6A2 3988/4885 |
| US-10428029-B2 | Isoxazole carboxamide compounds | SMYD3, SMYD2, SNRPD3 | TRPA1 4330/4885TAAR1 4061/4885SLC6A2 2148/4885 |
| US-20020119909-A1 | Preparation of enantiomerically enriched flavor and fragrance components | NISCH, FASTKD5, NOTUM | TRPA1 6/4885TAAR1 721/4885SLC6A2 4859/4885 |
| US-20170362217-A1 | Substituted Piperidine Compounds | SMYD3, SMYD2, SNRPD3 | TRPA1 2563/4885TAAR1 3266/4885SLC6A2 2009/4885 |
| US-20170190676-A1 | Isoxazole Carboxamide Compounds | SMYD3, SMYD2, SNRPD3 | TRPA1 4330/4885TAAR1 4061/4885SLC6A2 2148/4885 |
| US-20230219965-A1 | NITROGEN-CONTAINING FUSED BICYCLIC COMPOUNDS AND THEIR USE AS UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 1 (USP1) INHIBITORS | USP1, USP8, USP7 | TRPA1 4750/4885TAAR1 2828/4885SLC6A2 4447/4885 |
| US-20230203046-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AND SUBSTITUTED PURINES AND THEIR USE AS UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 1 (USP1) INHIBITORS | USP1, UPP1, USP2 | TRPA1 4618/4885TAAR1 3135/4885SLC6A2 3988/4885 |
| US-20170355695-A1 | SMYD Inhibitors | SMYD3, SMYD2, SMURF2 | TRPA1 4407/4885TAAR1 4417/4885SLC6A2 2309/4885 |
| US-20020177738-A1 | Novel optically active benzylalkylcarbinols, their preparation and use | CNR2, CNR1, PLD2 | TRPA1 827/4885TAAR1 2577/4885SLC6A2 3340/4885 |
| US-20170247326-A1 | Substituted Pyrrolidine Carboxamide Compounds | SMYD3, SMYD2, SMURF2 | TRPA1 4384/4885TAAR1 4268/4885SLC6A2 2638/4885 |
| US-20170362191-A1 | Substituted Cyclohexylamine Compounds | SMYD3, SMYD2, SNRPD3 | TRPA1 4005/4885TAAR1 2556/4885SLC6A2 613/4885 |
| US-20170253601-A1 | Substituted Pyrrolidine Compounds | SMYD2, SMYD3, SNRPD2 | TRPA1 4530/4885TAAR1 4226/4885SLC6A2 2219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.