Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.51 |
| ▸ | LCK | P06239 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | PRKACG | P22612 | 1/20 | 0.47 |
| ▸ | PRKACB | P22694 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PGAM1 | P18669 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23198967 | 0.88 | BCL2 (0.61) | ACLYELANELCKMAPTALDH1A1 | |
| 2-Methoxyanthraquinone SCHEMBL28176342 | 0.86 | MAPT (0.50) | ACLYELANELCKMAPTALDH1A1 | |
| SCHEMBL16226807 | 0.82 | ELANE (0.68) | ACLYELANELCKMAPTALDH1A1 | |
| SCHEMBL28232665 | 0.82 | PTPN1 (0.60) | ACLYELANELCKMAPTALDH1A1 | |
| SCHEMBL31237387 | 0.82 | TTR (0.66) | ACLYELANELCKMAPTALDH1A1 | |
| SCHEMBL22719980 | 0.82 | TTR (0.66) | ACLYELANELCKMAPTALDH1A1 | |
| SCHEMBL28872301 | 0.81 | PTPN1 (0.55) | ACLYELANELCKMAPTALDH1A1 | |
| SCHEMBL29066491 | 0.80 | LCK (0.54) | ACLYELANELCKMAPTALDH1A1 | |
| Rubiadin SCHEMBL22616292 | 0.80 | BCL2 (0.71) | ELANELCKMAPTALDH1A1GLA | |
| Rubiadin SCHEMBL1426928 | 0.80 | BCL2 (0.71) | ELANELCKMAPTALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115245533-B | Application of Nanshan flower root extract in treating pulmonary fibrosis | 中国医学科学院药物研究所 | 2023-07-28 | — | — | CN | claimed |
| CN-116585295-A | Application of Nanshan flower root extract in treating pulmonary fibrosis | 中国医学科学院药物研究所 | 2023-08-15 | — | — | CN | disclosed |
| CN-115245533-B | Application of Nanshan flower root extract in treating pulmonary fibrosis | 中国医学科学院药物研究所 | 2023-07-28 | — | — | CN | disclosed |