2-Methoxyanthraquinone

2-Methoxyanthraquinone

SCHEMBL28176342

COc1ccc2c(c1)C(=O)c1ccccc1C2=O.Cc1c(O)cc2c(c1C)C(=O)c1ccccc1C2=O

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
LCK P06239 3/20 0.50
ALDH1A1 P00352 2/20 0.50
GLA P06280 2/20 0.50
THRB P10828 1/20 0.50
LIMK1 P53667 1/20 0.50
LIMK2 P53671 1/20 0.50
AR P10275 1/20 0.50
MCL1 Q07820 4/20 0.48
BCL2 P10415 3/20 0.48
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
ELANE P08246 3/20 0.46
KDM4E B2RXH2 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
PGAM1 P18669 2/20 0.46
ACLY P53396 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29066488 0.86 ACLY (0.52) MAPTLCKALDH1A1GLATHRB
2-Methoxyanthraquinone SCHEMBL222927 0.81 PTPN1 (0.60) MAPTALDH1A1ARMCL1MEN1
SCHEMBL23198967 0.80 BCL2 (0.61) MAPTLCKALDH1A1GLATHRB
SCHEMBL4645032 0.79 PTPN1 (0.58) MAPTALDH1A1ARMCL1MEN1
SCHEMBL16227041 0.79 MAPT (0.68) MAPTLCKALDH1A1GLATHRB
SCHEMBL29066464 0.79 MAPT (0.63) MAPTLCKALDH1A1GLATHRB
SCHEMBL29066491 0.78 LCK (0.54) MAPTLCKALDH1A1GLAAR
SCHEMBL16227266 0.78 MAPT (0.67) MAPTLCKALDH1A1GLATHRB
SCHEMBL5999238 0.78 NTRK1 (0.51) MAPTLCKALDH1A1GLATHRB
SCHEMBL13239421 0.77 NPC1 (0.50) MAPTALDH1A1ARMCL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107281383-A A kind of compound pharyngitis preparation and preparation method thereof 云南蓝钻生物科技股份有限公司 2017-10-24 CN disclosed