Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 3/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | PRKACG | P22612 | 1/20 | 0.49 |
| ▸ | PRKACB | P22694 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451901 | 0.84 | CA1 (0.57) | LCKPRKACAPRKACGPRKACBESR1 | |
| SCHEMBL2252533 | 0.84 | CA1 (0.57) | LCKPRKACAPRKACGPRKACBESR1 | |
| SCHEMBL29173163 | 0.81 | ESR1 (0.67) | LCKPRKACAPRKACGPRKACBAR | |
| SCHEMBL23198984 | 0.81 | ELANE (0.68) | LCKESR1ESR2ELANEKDM4E | |
| Macrosporin SCHEMBL16227189 | 0.81 | ELANE (0.68) | LCKESR1ESR2ELANEKDM4E | |
| Macrosporin SCHEMBL30237810 | 0.81 | ELANE (0.68) | LCKESR1ESR2ELANEKDM4E | |
| SCHEMBL5810326 | 0.80 | LCK (0.56) | LCKPRKACAPRKACGPRKACBAR | |
| SCHEMBL29066488 | 0.80 | ACLY (0.52) | LCKPRKACAPRKACGPRKACBAR | |
| SCHEMBL10885799 | 0.80 | CA1 (0.53) | LCKPRKACAPRKACGPRKACBESR1 | |
| SCHEMBL30629120 | 0.80 | CA1 (0.57) | LCKPRKACAPRKACGPRKACBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115245533-B | Application of Nanshan flower root extract in treating pulmonary fibrosis | 中国医学科学院药物研究所 | 2023-07-28 | — | — | CN | claimed |
| CN-116585295-A | Application of Nanshan flower root extract in treating pulmonary fibrosis | 中国医学科学院药物研究所 | 2023-08-15 | — | — | CN | disclosed |
| CN-115245533-B | Application of Nanshan flower root extract in treating pulmonary fibrosis | 中国医学科学院药物研究所 | 2023-07-28 | — | — | CN | disclosed |