SCHEMBL29066973

SCHEMBL29066973

C=Cc1ccccc1C=C.CO[SiH3]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
TSHR P16473 2/20 0.38
KDM4E B2RXH2 2/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP3A4 P08684 1/20 0.35
NFE2L2 Q16236 3/20 0.34
TRPA1 O75762 1/20 0.34
CA4 P22748 2/20 0.33
LMNA P02545 2/20 0.33
HDAC8 Q9BY41 1/20 0.33
THRB P10828 1/20 0.33
BLM P54132 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL29277822 0.89 ALDH1A1 (0.52) ALDH1A1TSHRKDM4EMAPK1SMN1; SMN2
SCHEMBL8940327 0.89 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1SMN1; SMN2MEN1
SCHEMBL29066951 0.83 ALDH1A1 (0.48) ALDH1A1TSHRKDM4EMAPK1SMN1; SMN2
Ethane SCHEMBL29266735 0.83 ALDH1A1 (0.57) ALDH1A1TSHRMEN1KMT2ACYP3A4
SCHEMBL29405187 0.83 ALDH1A1 (0.63) ALDH1A1TSHRMEN1KMT2ANFE2L2
SCHEMBL473080 0.83 ALDH1A1 (0.63) ALDH1A1TSHRMEN1KMT2ANFE2L2
SCHEMBL7638 0.83 ALDH1A1 (0.63) ALDH1A1TSHRMEN1KMT2ANFE2L2
Methyl Alcohol SCHEMBL28639807 0.80 ALDH1A1 (0.55) ALDH1A1TSHRMAPK1MEN1KMT2A
Propene SCHEMBL7948571 0.80 ALDH1A1 (0.55) ALDH1A1TSHRMEN1KMT2ACYP3A4
SCHEMBL29022691 0.80 ALDH1A1 (0.44) ALDH1A1TSHRKDM4EMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN claimed