SCHEMBL8940327

SCHEMBL8940327

C=Cc1ccccc1C=C.[SiH3]O[SiH3]

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
TSHR P16473 2/20 0.41
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
BLM P54132 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP3A4 P08684 1/20 0.33
NFE2L2 Q16236 1/20 0.32
HPGD P15428 2/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29066973 0.89 ALDH1A1 (0.48) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL29405187 0.87 ALDH1A1 (0.63) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL7638 0.87 ALDH1A1 (0.63) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL473080 0.87 ALDH1A1 (0.63) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL9562250 0.84 ALDH1A1 (0.60) ALDH1A1TSHRMEN1KMT2ALMNA
Water SCHEMBL20379011 0.84 ALDH1A1 (0.60) ALDH1A1TSHRMEN1KMT2ALMNA
Ethylene SCHEMBL7946796 0.84 ALDH1A1 (0.60) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL1176773 0.84 ALDH1A1 (0.60) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL22496001 0.84 ALDH1A1 (0.60) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL11016199 0.84 ALDH1A1 (0.60) ALDH1A1TSHRMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111205788-B Anisotropic film and method for producing anisotropic film 信越化学工业株式会社 2024-06-07 CN disclosed
CN-108410174-A Poly- carbonate material and method 梅里奥创新公司 2018-08-17 CN disclosed
CN-105452190-B Polysilicate carbonate materials and methods 梅里奥创新公司 2018-04-24 CN disclosed
EP-0705296-A4 TELOMER COMPOSITION SOLA INT HOLDINGS (AU) 1996-07-03 EP disclosed
EP-0705296-A1 TELOMER COMPOSITION SOLA INTERNATIONAL HOLDINGS, LTD. (AU) 1996-04-10 EP disclosed
WO-1995000577-A1 TELOMER COMPOSITION SOLA INTERNATIONAL HOLDINGS LTD. (AU) 1995-01-05 WO disclosed