SCHEMBL29066979

SCHEMBL29066979

CCCCO[Si](CCC)(OCC)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.40
CYP1A2 P05177 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
ABCB1 P08183 1/20 0.35
TSHR P16473 3/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP19A1 P11511 1/20 0.34
RECQL P46063 1/20 0.32
FGFR1 P11362 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TLR8 Q9NR97 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL706281 0.95 LTA4H (0.43) LTA4HCYP1A2CYP2C9CYP2C19ABCB1
SCHEMBL19809151 0.90 LMNA (0.33) LTA4HLMNAALDH1A1
SCHEMBL19809308 0.90 LTA4H (0.43) LTA4HABCB1TSHRTP53NPC1
SCHEMBL706144 0.90 LTA4H (0.44) LTA4HCYP1A2CYP2C9CYP2C19ABCB1
SCHEMBL707895 0.89 LTA4H (0.32) LTA4HTP53MAPTALDH1A1
SCHEMBL29066985 0.88 LTA4H (0.41) LTA4HCYP1A2CYP2C9CYP2C19ABCB1
SCHEMBL707497 0.88 LTA4H (0.43) LTA4HCYP1A2CYP2C9CYP2C19ABCB1
SCHEMBL702248 0.88 LTA4H (0.43) LTA4HCYP1A2CYP2C9CYP2C19ABCB1
SCHEMBL710735 0.88 LTA4H (0.43) LTA4HCYP1A2CYP2C9CYP2C19ABCB1
SCHEMBL28867246 0.87 LTA4H (0.39) LTA4HABCB1TSHRTP53NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN disclosed