Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.38 |
| ▸ | ITGAV | P06756 | 17/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 8/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906558 | 0.93 | ITGB3 (0.41) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL2925954 | 0.90 | ITGB3 (0.40) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL2906764 | 0.82 | ITGB3 (0.47) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL2899491 | 0.81 | ITGB3 (0.50) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL2906110 | 0.80 | FAAH (0.38) | ITGB3ITGAVITGA2BITGB5F2R | |
| SCHEMBL2905461 | 0.80 | ITGB3 (0.34) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL12808312 | 0.79 | ITGB3 (0.40) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL2906935 | 0.79 | FAAH (0.38) | ITGB3ITGAVITGA2BITGB5F2R | |
| SCHEMBL2906882 | 0.77 | ITGB3 (0.47) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL2901789 | 0.75 | ITGB3 (0.37) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217569-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | Janssen Pharmaceutica N.V. (BE) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009058314-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-05-07 | — | — | WO | disclosed |